Searchable abstracts of presentations at key conferences in endocrinology

ea0015p287 | Reproduction | SFEBES2008

A study of the evaluation of elevated testosterone levels in women in a District General Hospital

Chandrashekar Harinath , Geen John , Baglioni Pierro

Introduction: There are numerous conditions which can cause elevated testosterone levels in women. PCOS being the commonest. Other causes include ovarian/adrenal androgen secreting tumours, CAH, Cushing syndrome, hyperprolactinemia, virilisation during pregnancy and finally idiopathic cause.Objectives: Our objective was to look into the way in which women with elevated testosterone were evaluated. We looked into why testosterone levels were done, who req...

ea0013p29 | Clinical practice/governance and case reports | SFEBES2007

Hyperkalemia in a district general hospital

Rajeev Surya P , Nair Satheesh B , Mahmood Muhammed Muzaffar , Geen John , Baglioni Piero

Objectives: To assess the aetiology and management of hyperkalemia amongst inpatients in a district general hospital.Methods: Individuals with hyperkalemia (defined as potassium>6.5 mmol/L) were identified from a biochemistry lab database. Review of case records in a six month period to assess the aetiology and management. Patients on renal replacement therapy and those<18 years were excluded.Results: 45 patients were ident...

ea0038p22 | Clinical biochemistry | SFEBES2015

Effect of cortisol assay bias on the overnight dexamethasone suppression test: implications for the investigation of Cushing’s syndrome

Brixey-McCann Rachel , Tennant Sarah , Geen John , Armston Annie , Barth Julian H , Keevil Brian , Rees Aled , Evans Carol

Background: NEQAS data demonstrate a divergence in bias of cortisol immunoassays over the last 10 years. Despite this, a serum cortisol of 50 nmol/l has been universally applied as the cut-off for the overnight dexamethasone suppression test (ONDST), the commonest screening test for Cushing’s syndrome.Aims: To assess the effect of assay bias on interpretation of the ONDST and determine the necessity for a method-specific cut-off.<p class="abstex...